Tag Archives: Otsuka

FRM-6124 Trials Halted

There is a highly credible report that the Forum Pharmaceuticals Phase III trials for encenicline/FRM-6124 are being halted due to a safety issue: Gastric hypomotility setting the stage for eventual gut perforation. FRM-6124 is a program that NIR has long … Continue reading

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A Momentary Lapse of Reason*

*Floyd, P.  1987 Every now and then, pharma/biotech companies do things that suggest that they had experienced a transient ischemic attack against their better judgment. Today there were two such events in the news: 1) Biogen-Idec and BIIB037 Biogen-Idec is … Continue reading

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Of Persistence and Ethics in Phase III

Persistence paid off for Lundbeck and Takeda, whose first Phase III program for their antidepressant Lu AA21004 failed. With revised dosing, they ran another extensive set of pivotal trials, have announced that they will be filing for regulatory approval in … Continue reading

Posted in Big Pharma, BioFollies | Tagged , , , , , , , | 1 Comment