Monthly Archives: March 2015

Aducanumab: Less Than Meets The Eye

The beta-amyloid target in Alzheimer’s has become, to put it politely, somewhat tarnished over the past several years. AN-1792, bapineuzumab, solanezumab, gantenerumab, plus several BACE and gamma-secretase inhibitors/modulators, have combined to form a conga-line of clinical disappointments, undulating its way … Continue reading

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NeuralStem ALS Results

NeuralStem’s results from their 15pt, open-label trial of neural stem cells (fetal source) in ALS proved to be both ambiguous and controversial. Since there was no control group, NeuralStem parsed the treatment sample into two cohorts, those who appeared to … Continue reading

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Targacept Finds Catalyst to Stop Its Bleeding

While not only not unexpected, but indeed inevitable, the news that Targacept is merging with Catalyst Biosciences (not to be confused–although it undoubtedly has been and will be–with Catalyst Pharmaceutical Partners) is an insipid and pathetic end to a story … Continue reading

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